The San Diego region has one of the highest concentrations of high-tech companies in the United States, and the third-highest concentration of biotech companies in the nation. A little known fact is that 95% of San Diego businesses are small and have fewer han 20 employees. This allows for flexibility and innovation. Small businesses need support from strategic industry associations to assist companies with a variety of issues. Some of the programs or agencies listed below were jump-started by the City, and the City works closely with all of the organizations.

• Access, Inc.
• Accessity
• Alliance SBDC
• Associated Builders & Contractors, Inc. - San Diego Chapter
• Associated General Contractors of America - San Diego Chapter, Inc.
• Better Business Bureau
• BIOCOM
• Black Contractors Association of San Diego
• Building Industry Association of San Diego
• Business for Good San Diego
• California Apartment Association of San Diego
• California Community & Place-Based Solutions
• California Department of Alcohol Beverage Control
• California Office of the Small Business Advocate
• California Restaurant Association
• Center for Applied Competitive Technologies - San Diego
• City Heights Community Development Corporation
• Chicano Federation
• Cleantech San Diego
• CONNECT
• Cyber Center of Excellence
• Hospital Association of San Diego & Imperial Counties
• Industrial Environmental Association of San Diego
• Jacobs Center for Neighborhood Innovation
• Karen Organization of San Diego
• Local Initiatives Support Corporation
• Metropolitan Area Advisory Committee (MAAC) Project
• Minority Business Development Agency
• Mission Edge
• NAIOP San Diego
• New Media Rights (California Western School of Law)
• Procurement Technical Assistance Center
• RISE San Diego
• San Diego Association of Governments
• San Diego Brewers Guild
• San Diego's Brewery Cluster
• San Diego Building Owners and Managers Association, Inc.
• San Diego County Apartment Association
• San Diego County Bar Association
• San Diego County Hotel-Motel Association
• San Diego Foundation
• San Diego Military Advisory Council
• San Diego MIT Enterprise Forum
• San Diego Port Tenants Association
• San Diego Ship Repair Association
• San Diego Sports Innovators
• San Diego Sports Commission
• San Diego & Imperial Small Business Development Center
• TMA BlueTech (formerly The Maritime Alliance)
• Union of Pan Asian Communities
• Urban Land Institute - San Diego/Tijuana Council
• World Trade Center San Diego
• Better Business Bureau
• Metropolitan Area Advisory Committee (MAAC) Project
• Regional Training Center
• San Diego Convention Center Corp.
• San Diego Contracting Opportunities Center (SDCOC)
• San Diego Metropolitan Transit System
• San Diego Tourism Authority
• San Diego Unified Port District
• San Diego Workforce Partnership
• South San Diego Small Business Development Center
• Small Business Law Center (Thomas Jefferson School of Law)
• Startup San Diego
• San Diego Volunteer Law Program