Throughout its history, the San Diego Fire-Rescue Department has encountered thousands of fires and incidents. Here are some of the major events:

• 1910 - American-Hawaiian Company Freighter Fire
• 1913 - The Great Standard Oil Fire
• 1925 - Brunswig Drug Company Fire
• 1948 - Goodrich Surplus Store Fire
• 1955 - Burnett Furniture Company
• 1956 - Fourth Alarm Kensington Fire
• 1957 - First Fifth Alarm Fire
• 1978 - Balboa Park - Aerospace Museum Fire - Old Globe Theatre
• 1978 - PSA Airliner Crash
• 1981 - First Sixth-Alarm Fire
• 1985 - Normal Heights Fire
• 2003 - Cedar Fire
• 2007 - Witch Creek/Guejito Fires